Research progress on endoscopic multimodal optical imaging

Endoscopic imaging, a minimally invasive and nondestructive biomedical imaging technology, has shown great potential in the diagnosis and treatment of natural cavity diseases. Endoscopic multimodal optical imaging combines the advantages of minimally invasive intervention via endoscopic systems with the high resolution, high contrast, and high imaging depth of multimodal optical imaging, providing a powerful means for precise imaging of deep tissues in the body. In recent years, with the deepening of research on endoscopic multimodal optical imaging systems and the expansion of biomedical application scenarios, this technology has shown excellent potential in both basic research and clinical applications. This article provides a comprehensive review of endoscopic multimodal optical imaging technology and research progress, aiming to provide direction for subsequent research on endoscopic multimodal optical imaging. This article first introduces endoscopic optical imaging technology; then, it reviews the research progress and corresponding clinical applications of endoscopic dual-mode, three-mode and four-mode optical imaging; and finally, it discusses the challenges and prospects of the future development of endoscopic multimodal optical imaging technology.